We have generated a novel monoclonal antibody targeting human FGFR1c (R1c mAb) that caused profound body weight and body fat loss in diet-induced obese mice due to decreased food intake (with energy expenditure unaltered), in turn improving glucose control.R1c mAb also caused weight loss in leptin-deficient ob/ob mice, leptin receptor-mutant db/db
The Increasing Significance of Religious Tourism: A Case from Uttar Pradesh, India
Tourism, in its numerous forms is a major source of income for various nations.India is no exception to this.Within some countries, a few states bring the major chunk of tourists.Uttar Pradesh is one such state for India which, on the virtue of its diversity, population and geographical size, has been at the forefront of attracting tourists from no
Frequency of pathology in a large natural sample from Natural Trap Cave with special remarks on erosive disease in the Pleistocene
The search for the Figurines antiquity of erosive arthritis was the subject of an international conference (1).Although isolated examples have been reported from the anthropologic record (2, 3), systemic population studies have represented a newer approach (4).Recognition of erosive disease, osteoarthritis and DISH, as isolated Tripod Stand observa